Wrong Turn (2003)

For years, the government wonders about the sudden disappearance of tourists in the West Virginia woods, but the fact that they was killed by genetic mutation bloodthirsty brothers. They have no name, only known as Three Finger, One-Eye and Saw-Tooth. The film resolves around 6 people trapped in the forest of Virginia. They realize there is something that is hunting them. Will they fight or run for their life?